Forgive me for asking, but what is different about this than Ubuntu 19.04? I looked through the POP!_OS (terrible name btw) promo page [1] and the majority of the things it's talking about are basic Gnome features shipped with Ubuntu?
That's a good question. Unfortunately I can't do System76 and Ubuntu guys justice here because I really don't know the work has been done in both distros.
From the user perspective, I would say
smoother hardware integration (I download the ISO with NVIDIA proprietary drivers, haven't encountered any graphic card comparability problem),
consistent theme across gtk and qt based applications ,
saner defaults and clearer setting structure,
good keyboard shortcuts. There are merely less than a dozen shortcuts that are not found in Ubuntu, but very easy to get used to. like win + up/down to switch between workspace.
I know all these can be accomplished by extensions, add-ons and themes. But they do feel different when it is out of the box and carefully curated.
[1] https://system76.com/pop