If you're referring to user-curated search result blocking, that's very easy with DuckDuckGo and uBlock Origin (just block elements like [data-domain="w3schools.com"]; see my comment to the GP). I don't know of any large extant lists like this though.
That won't do much if every result on the first page is blocked. Ideally a filter list like this could be pushed to the server side as a per-user preference to go with your query, so that if e.g. the top 10000 results were all filtered out, then you wouldn't have to click through (or infinite-scroll autoload) 100 empty pages before getting anything.
DDG will add more results, if enough are hidden. If I search "w3schools" with my filter, there are only two results on the first page that are not hidden, so it immediately displays the second page below. It seems that they planned for this use case.
