Works on my machine, anecdotally; no Wayland, and an X window manager that hasn't been updated in a decade. Automatically resizes windows when I drag them to fit each monitor's DPI settings.
Btw, does it allow you to run different scale on the different monitors? It wouldn't really be feasible to run native 4k resolution on one monitor if everything will be tiny, so it needs to have scale. One monitor might run on 1x and the other 2x.
