The biggest disadvantage in my mind of the Prusa MK2/3/4 printers is they use the original i3 design. It's a good design, and very simple to build, maintain and program. But it limits the print speed due to the amount of mass that has to move, particularly in the Y axis. The entire bed has to move which induces vibrations at higher speeds.
Newer printers (including the Prusa XL) use a CoreXY design, where the extruder is controlled in the X and Y axes by belts, which results in less mass that has to move, and allows the printer to print much, much faster. In the case of the Bambu Lab printers, it can be two to three times faster for a similar print quality.
CoreXY printers absolutely do have more stable kinematics for better acceleration, but modern open printer firmware--mostly Klipper, though you can do it with Marlin in an unsatisfying way--implements resonance compensation, aka input shaping, in a way that really improves acceleration (which matters way more than top speed for most prints).
My Sovol SV06 can make a really nice-quality 3DBenchy in 37 minutes after doing my input shaping samples. That's not as fast as an X1 Carbon, but it cost a quarter as much, and I tend to think that when it comes to 3D printers that bandwidth is more valuable than latency.
I'll take the slower printer speed if it means I get better reliability, repeatability and repearability. Any day.
I've wasted enough hours on fancy features/materials/settings that don't work. Couldn't care less about the feature of being able to print a part a few minutes/hours faster tbh.
Years ago people were talking how delta printers were so much better, faster, cheaper, etc than bedslingers. Years later people forgot about delta printers and now its core-xy. Meanwhile bedslingers continue to just work.
I could care less if you printer goes 50% faster if it fails even 5% more.
Heck, I'm still using my ancient Rostock Max, and it works just fine for my needs. It's such a stable platform that I haven't had to re-zero the bed in months. Once it's up to temp, it's in spec. My only wish-I-had was the ability to use a wider variety of filament, but the bowden tube is just too long for any of the specialty mixes. No issues at all with PLA, though!
Newer printers (including the Prusa XL) use a CoreXY design, where the extruder is controlled in the X and Y axes by belts, which results in less mass that has to move, and allows the printer to print much, much faster. In the case of the Bambu Lab printers, it can be two to three times faster for a similar print quality.