Yes! Now we are getting on to the true cost of advanced tickets.
Fines for making mistakes, rebooking fees, rebooking and having to pay a higher fare, lost tickets because sometimes it's just easier to book a new ticket, losing out when unwell etc...
I bet they make a tidy sum from unused advance tickets
(Great Britain specific):
Although worth noting when it's out of your control the railway does have to offer you options. You don't have 100% of the liability.
And if your train is cancelled you're entitled to take the one before/after for example or get a refund
I'd say half of the advanced purchased journeys end up costing me more than just booking the train the day of.