B6 is the IATA designator for JetBlue. People who travel heavily, or otherwise spend a lot of time talking about airlines, often use these to refer to airlines rather than writing out the full names over and over.
IATA designators for commonly-discussed US-based airlines:
Yeah, definitely appropriate abbreviation for the airplane nuts at Hacker News. It's an interesting TIL, but for future reference, @WildUtah, I'd wager less than 1% of the population knows anything about airline designations.
I wouldn't say they're common knowledge either. Sure, when ones traveling they may notice their abbreviation, but beyond a glance, it's not of much import to most.
Maybe overseas, but I've never seen IATA airlines codes used on an arrival/departure board in the US. Is the US we just spell out the airline, there are plenty of pixels.