Control isn't necessary - I'm not sure why it would be specified. On a laptop you might have to hold the Fn key to hit PrtScr, but aside from that it's two fingers to hit 'Right Alt' and 'PrtScr' and the other hand can mash r,e,i,s,u,b.
In my workplace I have a Dell Keyboard that has the SysRq/Scroll Lock/Pause Keys on the top right, above the numpad. Holding Alt+SysRq with one hand is just impossible.
Yeah, with a typical ANSI layout it's a small stretch but definitely doable.
This is the layout that I have (and the only keyboard layout I'll ever buy, because every other throws the pipe key and backslash in a random spot along with randomly sizing the enter key)
I think I need an extra hand to do this