mlost - There are some great responses in this thread and hopefully you're feeling supported. The comment you made about it being a "distress call" really grabbed my attention and if you're in the SF area I'd be happy to buy you a coffee/beer and talk about this or whatever you want.

I've been in a similar situation and can relate to the cocktail of hope/anxiety/despair that come with entrepreneurship and the quarter-life crisis. If you're interested: david [at] moctopus [dot] com